Database/Skin Conditioning/Heptapeptide-8
100% natural origin · ISO 16128

Is Heptapeptide-8 natural?

Yes. All residues are amino acids from fermentation or protein hydrolysate; synthesis reagents and protecting groups leave no mass in the final peptide.

INCI nameHeptapeptide-8
FunctionSkin Conditioning
FeedstockFermentation-derived amino acids are coupled by solid-phase peptide…

How we scored it

7-residue peptide from Arg, Ile, Leu, Phe (CosIng); no cap listed; all residues natural amino acids; full mass natural, 1.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Fermentation-derived amino acids are coupled by solid-phase peptide synthesis into the seven-residue chain. No alternative route is significant.

In plain English

A synthetic chain of seven amino acids used to condition skin. It is assembled in a lab from amino acids that are normally produced by fermentation.

CosIng definition: Heptapeptide-8 is the synthetic peptide consisting of arginine, isoleucine, leucine and phenylalanine

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2HEPTAPEPTIDE-8. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  3. 3HEPTAPEPTIDE-8. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=HEPTAPEPTIDE-8