Database/Skin Conditioning/Harpagoside
100% natural origin · ISO 16128

Is Harpagoside natural?

Yes. Extracted/purified from Harpagophytum procumbens root; no synthetic fragment present.

INCI nameHarpagoside
CAS19210-12-9
FormulaC24H30O11 · 494.5 Da
FunctionSkin Conditioning
FeedstockIsolated by extraction and purification from the roots…

How we scored it

Iridoid glycoside isolated from Devil's Claw root; entirely plant-derived (sugar and aglycone both botanical).
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Isolated by extraction and purification from the roots of Devil's Claw (Harpagophytum procumbens). No synthetic production route is used commercially.

In plain English

A natural compound extracted from Devil's Claw root, used as a skin-conditioning ingredient. It's purified directly from the plant.

Structure

2D structure of Harpagoside

[(1S,4aS,5R,7S,7aS)-4a,5-dihydroxy-7-methyl-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,5,6,7a-tetrahydrocyclopenta[c]pyran-7-yl] (E)-3-phenylprop-2-enoate

PubChem CID 5281542 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Harpagoside. PubChem CID 5281542. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3HARPAGOSIDE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4HARPAGOSIDE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=HARPAGOSIDE