Database/Opacifying/Guanosine
100% natural origin · ISO 16128

Is Guanosine natural?

Yes. Produced by microbial fermentation of sugar feedstocks, the standard route for cosmetic-grade nucleosides.

INCI nameGuanosine
CAS118-00-3
FormulaC10H13N5O5 · 283.24 Da
FunctionOpacifying · Skin Conditioning
FeedstockGuanosine is manufactured by fermentation of glucose using…

How we scored it

Nucleoside C10H13N5O5: ribose + guanine, both fermentation-derived. 1.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Guanosine is manufactured by fermentation of glucose using purine-producing microorganisms. This is the dominant commercial route for cosmetic grade.

In plain English

Guanosine is a nucleoside that conditions skin and helps products stay opaque. It's made by fermenting plant sugars with microorganisms.

Structure

2D structure of Guanosine

2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one

PubChem CID 135398635 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Guanosine. PubChem CID 135398635. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3GUANOSINE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4GUANOSINE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=GUANOSINE