Database/Skin Conditioning/Glucuronolactone
100% natural origin · ISO 16128

Is Glucuronolactone natural?

Yes. Lactone of D-glucuronic acid made by oxidising corn-starch glucose; every atom in the ring traces to the starch feedstock.

INCI nameGlucuronolactone
CAS32449-92-6
FormulaC6H8O6 · 176.12 Da
FunctionSkin Conditioning
FeedstockManufactured by oxidation of glucose derived from corn…

How we scored it

C6H8O6, MW176: all 6 C trace to D-glucose (starch-derived); oxidation to the lactone uses reagents that leave no mass in the product → 176/176 = 1.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Manufactured by oxidation of glucose derived from corn or other starch. No petrochemical production route is used commercially.

In plain English

A sugar-derived ingredient made from cornstarch glucose, used to condition skin. It occurs naturally in the body and plants, and is produced industrially by a simple oxidation of plant sugar.

CosIng definition: D-Glucuronic acid, .gamma.-lactone

Structure

2D structure of Glucuronolactone

(2R)-2-[(2S,3R,4S)-3,4-dihydroxy-5-oxooxolan-2-yl]-2-hydroxyacetaldehyde

PubChem CID 92283 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Glucuronolactone. PubChem CID 92283. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3GLUCURONOLACTONE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4GLUCURONOLACTONE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=GLUCURONOLACTONE