How we scored it
Isoflavan isolated by extraction/purification from Glycyrrhiza glabra (liquorice) root; no commercially significant total-synthesis route. 1.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.
Where it comes from
Glabridin is extracted and purified from liquorice (Glycyrrhiza glabra) root. Complex total synthesis is not used commercially for cosmetic-grade material.
In plain English
A skin-brightening compound extracted from liquorice root. It is isolated and purified from the root using standard extraction methods rather than built chemically from scratch.
Structure
4-[(3R)-8,8-dimethyl-3,4-dihydro-2H-pyrano[2,3-f]chromen-3-yl]benzene-1,3-diol
References
- 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
- 2Glabridin. PubChem CID 124052. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
- 3GLABRIDIN. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
- 4GLABRIDIN. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=GLABRIDIN