Database/Anti-Seborrheic/Ethyl Lauroyl Arginate HCl
100% natural origin · ISO 16128

Is Ethyl Lauroyl Arginate HCl natural?

Yes. Built from fermentation arginine, coconut-derived lauric acid, and ethanol, salted with HCl; all building blocks natural if ethanol is bio-based.

INCI nameEthyl Lauroyl Arginate HCl
CAS60372-77-2
FormulaC20H41ClN4O3 · 421.0 Da
FunctionAnti-Seborrheic · Hair Conditioning
FeedstockMade by esterifying and N-acylating fermentation-derived arginine with…

How we scored it

Arginine (fermentation) 174.2 + lauric acid (natural, C12) 200.3 + ethanol (assumed fermentation) 46.1 − 2 H2O (amide+ester) + HCl (mineral) = 421.0; all fragments natural = 1.0
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

How it’s made

Arginine ethyl ester acylated by lauroyl chloride (Schotten–Baumann). Each curved arrow moves one electron pair, and the film ends on the score above.

Where it comes from

Made by esterifying and N-acylating fermentation-derived arginine with lauric acid from coconut/palm kernel oil, then forming the HCl salt. The ethanol used can also be petrochemical, which would lower this value.

In plain English

A preservative and conditioning ingredient built from an amino acid, coconut fatty acid, and alcohol. Used in cosmetics and personal care to help control microbial growth.

CosIng definition: Ethyl Lauroyl Arginate HCl is the salt that conforms to the formula:

Structure

2D structure of Ethyl Lauroyl Arginate HCl

ethyl (2S)-5-(diaminomethylideneamino)-2-(dodecanoylamino)pentanoate;hydrochloride

PubChem CID 25229630 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Ethyl Lauroyl Arginate HCl. PubChem CID 25229630. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3ETHYL LAUROYL ARGINATE HCL. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4ETHYL LAUROYL ARGINATE HCL. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=ETHYL%20LAUROYL%20ARGINATE%20HCL