Database/Skin Conditioning/Dipeptide-8
100% natural origin · ISO 16128

Is Dipeptide-8 natural?

Yes. Peptide-coupled from two fermentation/hydrolysate-derived amino acids; synthesis leaves no added mass.

INCI nameDipeptide-8
FormulaC8H14N2O4 · 202.21 Da
FunctionSkin Conditioning
FeedstockMade by peptide synthesis from alanine and hydroxyproline,…

How we scored it

Synthetic dipeptide of alanine and hydroxyproline, both natural-origin amino acids; fully natural.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Made by peptide synthesis from alanine and hydroxyproline, both produced by fermentation or protein hydrolysis.

In plain English

A lab-made two-amino-acid peptide used to condition skin, built from alanine and hydroxyproline, both naturally sourced via fermentation or protein hydrolysis.

CosIng definition: Dipeptide-8 is a synthetic peptide consisting of alanine and hydroxyproline

Structure

2D structure of Dipeptide-8

(2S,4R)-1-[(2S)-2-aminopropanoyl]-4-hydroxypyrrolidine-2-carboxylic acid

PubChem CID 25227058 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Dipeptide-8. PubChem CID 25227058. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3DIPEPTIDE-8. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4DIPEPTIDE-8. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=DIPEPTIDE-8