Database/Skin Conditioning/Dipeptide-8 HCl
100% natural origin · ISO 16128

Is Dipeptide-8 HCl natural?

Yes. Amino acids are fermentation products and the hydrochloride counter-ion is mineral; the exact dipeptide sequence is not stated in the batch data.

INCI nameDipeptide-8 HCl
FunctionSkin Conditioning
FeedstockTwo fermentation-derived amino acids are coupled by peptide…

How we scored it

Dipeptide identity not given; two amino acids (fermentation or hydrolysate) plus ionic chloride from HCl (mineral); no caps or petrochemical atoms assumed. 1.00.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Two fermentation-derived amino acids are coupled by peptide synthesis, with protecting groups and coupling agents leaving no mass, and isolated as the hydrochloride. A residue made solely by chemical synthesis would lower the value.

In plain English

A short chain of two amino acids supplied as its hydrochloride salt and used as a skin-conditioning ingredient in serums and creams. The peptide is assembled from amino acids that are made by fermentation.

CosIng definition: Dipeptide-8 HCl is the hydrochloride salt of Dipeptide-8

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2DIPEPTIDE-8 HCL. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  3. 3DIPEPTIDE-8 HCL. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=DIPEPTIDE-8%20HCL