Database/Skin Conditioning/Dipeptide-4
100% natural origin · ISO 16128

Is Dipeptide-4 natural?

Yes. Both residues are fermentation-derived amino acids; the peptide bond adds no petrochemical mass.

INCI nameDipeptide-4
CAS19246-18-5
FormulaC5H10N2O3S · 178.21 Da
FunctionSkin Conditioning
FeedstockMade by joining cysteine and glycine, fermentation-derived amino…

How we scored it

Dipeptide of cysteine+glycine (C5H10N2O3S=178.2 matches); condensation water lost only → 1.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Made by joining cysteine and glycine, fermentation-derived amino acids, via a peptide bond. No petrochemical route is used.

In plain English

A simple two-amino-acid peptide, from cysteine and glycine, used to condition skin. Built by linking two naturally sourced amino acids together.

CosIng definition: Dipeptide-4 is a synthetic peptide consisting of cysteine and glycine; Cysteine, synthetic dipeptide with glycine

Structure

2D structure of Dipeptide-4

2-[[(2R)-2-amino-3-sulfanylpropanoyl]amino]acetic acid

PubChem CID 439498 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Dipeptide-4. PubChem CID 439498. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3DIPEPTIDE-4. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4DIPEPTIDE-4. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=DIPEPTIDE-4