How we scored it
Gly C2H5NO2 75.1 x 2 - H2O 18.0 = C4H8N2O3 132.1 Da (glycylglycine), matching description; all amino-acid mass counted natural (n = 1) by this site's convention. 132.1 / 132.1 = 1.00.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.
Where it comes from
Dominant route couples glycine into the dipeptide by peptide synthesis, with protecting groups and coupling agents leaving no mass. Glycine itself comes from protein hydrolysis or fermentation, but much commercial glycine is synthesised from chloroacetic acid and ammonia; the site's amino-acid convention counts it as natural.
In plain English
A very short chain of two glycine molecules (glycylglycine) joined together, used in hair- and skin-care products as a conditioning ingredient. Glycine, the simplest amino acid, is obtained from protein hydrolysis or fermentation, or made chemically, and the pair is linked in a laboratory.
CosIng definition: Dipeptide-15 is the synthetic peptide consisting of glycine.
Structure
2-[(2-aminoacetyl)amino]acetic acid
References
- 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
- 2Dipeptide-15. PubChem CID 11163. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
- 3DIPEPTIDE-15. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
- 4DIPEPTIDE-15. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=DIPEPTIDE-15