How we scored it
Ala C3H7NO2 89.1 + Thr C4H9NO3 119.1 - H2O 18.0 = C7H14N2O4 190.2 Da, matching the description; all amino-acid mass is natural (n = 1). 190.2 / 190.2 = 1.00.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.
Where it comes from
Dominant route is coupling of fermentation-derived L-alanine and L-threonine by solution-phase or solid-phase peptide synthesis. Protecting groups, coupling agents and solvents leave no mass in the product, so no petrochemical fragment remains.
In plain English
A very short chain of two amino acids, alanine and threonine, joined together and used as a peptide ingredient in cosmetics. The amino acids are made by fermenting sugars or from protein hydrolysates, then linked together by chemical synthesis in a laboratory.
CosIng definition: Dipeptide-14 is the synthetic peptide consisting of alanine and threonine.
Structure
(2S,3R)-2-[[(2S)-2-aminopropanoyl]amino]-3-hydroxybutanoic acid
References
- 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
- 2Dipeptide-14. PubChem CID 6427004. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
- 3DIPEPTIDE-14. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
- 4DIPEPTIDE-14. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=DIPEPTIDE-14