Database/Skin Conditioning/Diosgenin
100% natural origin · ISO 16128

Is Diosgenin natural?

Yes. Isolated and hydrolysed from Dioscorea/Trigonella plant saponins; no petrochemical fragment in the final steroid skeleton.

INCI nameDiosgenin
CAS512-04-9
FormulaC27H42O3 · 414.6 Da
FunctionSkin Conditioning
FeedstockProduced by acid hydrolysis of saponins extracted from…

How we scored it

Single phytosteroidal sapogenin obtained by acid hydrolysis of saponins from yam/fenugreek; all carbons plant-derived, hydrolysis water not counted.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Produced by acid hydrolysis of saponins extracted from wild yam (Dioscorea) tubers or fenugreek (Trigonella) seeds. It is also a precursor for semi-synthetic steroids, but as supplied here it is the natural plant isolate.

In plain English

A plant-derived compound found in yams and fenugreek seeds, used in skincare for skin conditioning. It's obtained by extracting and hydrolysing natural plant saponins, not by chemical synthesis.

Structure

2D structure of Diosgenin

(1S,2S,4S,5'R,6R,7S,8R,9S,12S,13R,16S)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2'-oxane]-16-ol

PubChem CID 99474 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Diosgenin. PubChem CID 99474. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3DIOSGENIN. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4DIOSGENIN. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=DIOSGENIN