Database/Skin Conditioning/Diacetyl Boldine
Mostly natural · ISO 16128

Is Diacetyl Boldine natural?

Mostly. Boldine is a natural alkaloid extracted from boldo bark or leaves; the two acetyl caps come from petrochemical acetic anhydride.

INCI nameDiacetyl Boldine
CAS72584-75-9
FormulaC23H25NO6 · 411.4 Da
FunctionSkin Conditioning
FeedstockBoldine is extracted from Peumus boldus bark or…

How we scored it

Boldine core C19H21NO4 (327.4 Da, natural alkaloid) / total C23H25NO6 (411.4 Da); two acetate caps C4H4O2 (84.0 Da) from acetic anhydride are petrochemical. 327.4/411.4=0.80.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Boldine is extracted from Peumus boldus bark or leaves, then chemically diacetylated with acetic anhydride to improve stability. The alkaloid skeleton is plant-derived; the acetate esters are synthetic.

In plain English

A skin-conditioning ingredient made by chemically modifying boldine, an alkaloid extracted from boldo tree bark and leaves, with two acetate groups. Combines a plant-derived core with synthetic acetate caps.

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Structure

2D structure of Diacetyl Boldine

[(6aS)-9-acetyloxy-1,10-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-2-yl] acetate

PubChem CID 11732365 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Diacetyl Boldine. PubChem CID 11732365. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3DIACETYL BOLDINE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4DIACETYL BOLDINE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=DIACETYL%20BOLDINE