Database/Skin Conditioning/Decapeptide-5
100% natural origin · ISO 16128

Is Decapeptide-5 natural?

Yes. All nine amino acids are fermentation/hydrolysate-derived; synthesis reagents and protecting groups contribute no atoms to the final peptide.

INCI nameDecapeptide-5
FunctionSkin Conditioning
FeedstockMade by solid-phase synthesis from fermentation-derived amino acids.…

How we scored it

Peptide built only from natural amino acids (Asp, Cys, Gly, Glu, His, Ile, Met, Ser, Tyr); coupling reagents leave no mass. 1.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Made by solid-phase synthesis from fermentation-derived amino acids. No alternative commercial route changes this.

In plain English

A lab-assembled chain of natural amino acids used to help condition skin. Although it is manufactured, every building block comes from fermentation, so it counts as fully natural-origin.

CosIng definition: Decapeptide-5 is the synthetic peptide consisting of aspartic acid, cysteine, glycine, glutamic acid, histidine, isoleucine, methionine, serine and tyrosine

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2DECAPEPTIDE-5. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  3. 3DECAPEPTIDE-5. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=DECAPEPTIDE-5