How we scored it
Synthetic peptide of Arg/Lys/Ser/Trp/Tyr; amino-acid building blocks plus coupling chemistry leaves no mass.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.
Where it comes from
Solid-phase synthesised from five natural amino acids. No alternative route noted.
In plain English
A lab-assembled chain of 5 amino acids used as a skin-conditioning and brightening ingredient. It's built from the same amino acids found throughout nature.
CosIng definition: Decapeptide-12 is a synthetic peptide consisting of arginine, lysine, serine, tryptophan, and tyrosine
Structure
2-[[2-[[2-[[2-[[2-[[6-amino-2-[[2-[[2-[[2-[[2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-hydroxypropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]hexanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxypropanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-(4-hydroxyphenyl)propanoic acid
References
- 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
- 2Decapeptide-12. PubChem CID 25087629. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
- 3DECAPEPTIDE-12. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
- 4DECAPEPTIDE-12. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=DECAPEPTIDE-12