Database/Anti-Seborrheic/Ciclopirox Olamine
100% petroleum · ISO 16128

Is Ciclopirox Olamine natural?

No. Ciclopirox is built from petrochemical cyclohexyl and pyridone intermediates, and ethanolamine comes from ethylene oxide and ammonia.

INCI nameCiclopirox Olamine
CAS41621-49-2
FormulaC14H24N2O3 · 268.35 Da
FunctionAnti-Seborrheic · Antimicrobial
FeedstockFully synthetic active made by pyridone ring synthesis…

How we scored it

Ciclopirox C12H17NO2 207.3 and ethanolamine C2H7NO 61.1 are both fully synthetic; 0 / 268.4 = 0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Fully synthetic active made by pyridone ring synthesis and N-hydroxylation, then salted with ethanolamine from ethylene oxide. No natural route exists.

In plain English

A synthetic antifungal and anti-dandruff agent used in medicated shampoos and scalp treatments, supplied as a salt with ethanolamine. Both the ciclopirox and the ethanolamine are made from petrochemical raw materials.

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Structure

2D structure of Ciclopirox Olamine

2-aminoethanol;6-cyclohexyl-1-hydroxy-4-methylpyridin-2-one

PubChem CID 38911 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Ciclopirox Olamine. PubChem CID 38911. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3CICLOPIROX OLAMINE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4CICLOPIROX OLAMINE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=CICLOPIROX%20OLAMINE