Database/Skin Conditioning/Cholesteryl Oleate
100% natural origin · ISO 16128

Is Cholesteryl Oleate natural?

Yes. Cholesterol from wool grease is esterified with oleic acid from vegetable oil; both feedstocks are natural, so the ester is fully natural-origin.

INCI nameCholesteryl Oleate
CAS303-43-5
FormulaC45H78O2 · 651.1 Da
FunctionSkin Conditioning
FeedstockMade by esterifying wool-grease (lanolin) derived cholesterol with…

How we scored it

Cholesterol 386.65 (natural sterol) + oleic acid 282.47 (natural fatty acid) minus H2O 18.02 = 651.1. Both fragments natural-origin, so 651.1/651.1 = 1.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Made by esterifying wool-grease (lanolin) derived cholesterol with oleic acid from a vegetable oil such as sunflower or olive. A plant-sterol bioconversion route to cholesterol is a less common alternative.

In plain English

A skin-conditioning ingredient made by combining a natural sterol from wool grease with oleic acid, a fatty acid from vegetable oil. It helps soften and smooth the skin's surface.

Structure

2D structure of Cholesteryl Oleate

[(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] (Z)-octadec-9-enoate

PubChem CID 5283632 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Cholesteryl Oleate. PubChem CID 5283632. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3CHOLESTERYL OLEATE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4CHOLESTERYL OLEATE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=CHOLESTERYL%20OLEATE