Database/Antiplaque/Cetylamine Hydrofluoride
Mostly natural · ISO 16128

Is Cetylamine Hydrofluoride natural?

Mostly. The C16 chain comes from palm or coconut fatty acid, fluoride from mineral fluorspar, and the amine nitrogen from natural-gas ammonia, which is treated as petrochemical.

INCI nameCetylamine Hydrofluoride
CAS3151-59-5
FormulaC16H36FN · 261.46 Da
FunctionAntiplaque · Oral Care
FeedstockFatty acid is converted with ammonia to the…

How we scored it

C16H36FN (261.5 Da): hexadecyl C16H33 225.4 Da from palm/coconut fatty acid (natural); HF 20.0 Da from fluorspar (mineral); NH2 16.0 Da from natural-gas ammonia (0); 245.4 / 261.5 = 0.94.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Fatty acid is converted with ammonia to the nitrile and hydrogenated to hexadecylamine, then neutralised with hydrofluoric acid made from fluorspar. Petrochemical Ziegler-derived C16 chains exist, so a supplier note applies.

In plain English

A fatty amine salt of hydrofluoric acid used in oral-care products as a fluoride source with antiplaque function. The C16 amine comes from palm or coconut fatty acids and the fluoride from mineral fluorspar.

Natural alternatives with the same function

Aluminum Fluoride 100% natural origin

A mineral salt used in some oral-care products to help protect teeth, supplying fluoride and aluminium ions.

 Calcium Fluoride 100% natural origin

A mineral ingredient used in oral-care products to help protect teeth. It is the same mineral found in…

 Calcium Glycerophosphate 100% natural origin

A calcium salt built from glycerin and mineral phosphate. Used in oral care products to help protect tooth…

 Calcium Monofluorophosphate 100% natural origin

A mineral salt of calcium, phosphate and fluoride used in toothpaste as a fluoride source and antiplaque agent.…

 Calcium Phosphate 100% natural origin

Used in toothpaste as a mild abrasive, buffer and bulking agent that also helps fight plaque. It's a…

 Carboxylesterase 100% natural origin

An enzyme that splits ester bonds, listed for use in oral care products against plaque. Enzymes are proteins…

Structure

2D structure of Cetylamine Hydrofluoride

hexadecan-1-amine;hydrofluoride

PubChem CID 18471 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Cetylamine Hydrofluoride. PubChem CID 18471. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3CETYLAMINE HYDROFLUORIDE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4CETYLAMINE HYDROFLUORIDE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=CETYLAMINE%20HYDROFLUORIDE