Database/Skin Conditioning/Cetyl Tranexamate Mesylate
Mostly petroleum · ISO 16128

Is Cetyl Tranexamate Mesylate natural?

Mostly not. Fatty cetyl ester group is oleochemical; the tranexamic-acid core and methanesulfonate salt are both synthetic, petrochemical fragments.

INCI nameCetyl Tranexamate Mesylate
CAS2644725-65-3
FormulaC25H51NO5S · 477.7 Da
FunctionSkin Conditioning
FeedstockThe cetyl ester group comes from coconut/palm fatty…

How we scored it

Cetyl C16H33 (225.4, natural) vs tranexamate core (cyclohexane+aminomethyl+carbonyl, 157.2, petrochemical, toluene-route) + mesylate CH3SO3 (95.1, petrochemical) = 225.4/477.7 = 0.47.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

The cetyl ester group comes from coconut/palm fatty alcohol; the tranexamate core is a synthetic pharmaceutical-derived cyclohexane compound made industrially from toluene derivatives, salted with petrochemical methanesulfonic acid.

In plain English

A manufactured ingredient combining a coconut/palm-derived fatty alcohol with a synthetic compound related to tranexamic acid. Used in serums for skin conditioning and to help even out skin tone.

CosIng definition: Cetyl Tranexamate Mesylate is the organic compound that conforms to the formula:

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Structure

2D structure of Cetyl Tranexamate Mesylate

(4-hexadecoxycarbonylcyclohexyl)methylazanium;methanesulfonate

PubChem CID 177843933 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Cetyl Tranexamate Mesylate. PubChem CID 177843933. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3CETYL TRANEXAMATE MESYLATE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4CETYL TRANEXAMATE MESYLATE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=CETYL%20TRANEXAMATE%20MESYLATE