Database/Skin Conditioning/Cetyl-PG Hydroxyethyl Palmitamide
Mostly natural · ISO 16128

Is Cetyl-PG Hydroxyethyl Palmitamide natural?

Mostly. Palmitic acid and cetyl alcohol are oleochemical; ethanolamine (ethylene oxide plus ammonia) and the glycidyl/propylene-glycol link are petrochemical.

INCI nameCetyl-PG Hydroxyethyl Palmitamide
CAS110483-07-3
FormulaC37H75NO4 · 598.0 Da
FunctionSkin Conditioning
FeedstockPalmitic acid and cetyl alcohol from palm or…

How we scored it

Natural: palmitoyl C16H31O 239.4 + cetyloxy C16H33O 241.4 = 480.9. Petrochemical: N-hydroxyethyl 45.1 + N 14.0 + hydroxypropyl C3H6O 58.1 = 117.1. 480.9 / 598.0 = 0.80.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Palmitic acid and cetyl alcohol from palm or coconut oil are joined through ethanolamine and a glycidyl ether linker to build this ceramide-like amide. The linker is treated as petrochemical even where glycerin-based epichlorohydrin is used.

In plain English

A ceramide-like lipid used to condition skin, built from two fatty chains (palmitic acid and cetyl alcohol) joined by a small nitrogen-containing linker. The fatty parts come from palm or coconut oil; the linker is synthetic.

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Structure

2D structure of Cetyl-PG Hydroxyethyl Palmitamide

N-(3-hexadecoxy-2-hydroxypropyl)-N-(2-hydroxyethyl)hexadecanamide

PubChem CID 3082568 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Cetyl-PG Hydroxyethyl Palmitamide. PubChem CID 3082568. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3CETYL-PG HYDROXYETHYL PALMITAMIDE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4CETYL-PG HYDROXYETHYL PALMITAMIDE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=CETYL-PG%20HYDROXYETHYL%20PALMITAMIDE