Database/Hair Conditioning/Ceramide EOS
Route-dependent · ISO 16128

Is Ceramide EOS natural?

It depends. CosIng describes this ceramide as synthetic, and the same sphingoid-base question that makes Ceramide NG and Ceramide 2 route-dependent applies here too. Scoring it as fully renewable assumes the natural-feedstock build without evidence that it dominates.

INCI nameCeramide EOS
CAS156170-27-3
FormulaC66H125NO5 · 1012.7 Da
FunctionHair Conditioning · Skin Conditioning
FeedstockMade by linking a sphingosine-type backbone to a…

Why the score varies

This ingredient is made commercially by more than one route, and ISO 16128 scores the feedstock actually used. Without a supplier certificate of origin the value cannot be claimed.

RouteFeedstockNOIShareNotes
fermentation-derived sphingoid base + natural fatty acidsyeast/glucose fermentation plus plant fatty acids1.00~40%
total chemical synthesispetrochemical aldehydes and alkenes0.00~60%
Ask your supplier. A batch-specific certificate of origin or bio-based carbon test (ASTM D6866) settles which route applies.

How we scored it

Ceramide EOS is C66H125NO5. As with the other ceramides, no fragment split applies: if the sphingoid base and both fatty acid chains come from fermentation and plant oils the whole molecule is natural, 1.00; if the base is built by total chemical synthesis from petrochemical intermediates the value is 0.00.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Made by linking a sphingosine-type backbone to a fatty-acid-esterified omega-hydroxy acid. The sphingoid base is either fermentation-derived or built by total chemical synthesis, and CosIng does not record which feedstock chain is used.

In plain English

A lipid used in barrier-repair moisturisers to help reinforce the skin's outer protective layer. It is manufactured through chemical synthesis by linking a sphingosine-type backbone with a long-chain fatty-acid ester; its exact feedstocks are not fully disclosed.

CosIng definition: Ceramide EOS is a synthetic N-acylated sphingolipid consisting of Sphingosine having the D-erythro structure linked to an esterified omega-hydroxy saturated or unsaturated fatty acid

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Structure

2D structure of Ceramide EOS

[30-[[(E,2S,3R)-1,3-dihydroxyoctadec-4-en-2-yl]amino]-30-oxotriacontyl] (9Z,12Z)-octadeca-9,12-dienoate

PubChem CID 5282311 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Ceramide EOS. PubChem CID 5282311. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3CERAMIDE EOS. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4CERAMIDE EOS. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=CERAMIDE%20EOS