Why the score varies
This ingredient is made commercially by more than one route, and ISO 16128 scores the feedstock actually used. Without a supplier certificate of origin the value cannot be claimed.
| Route | Feedstock | NOI | Share | Notes |
|---|---|---|---|---|
| fermentation-derived sphingoid base + natural fatty acid | yeast/glucose fermentation plus plant fatty acid | 1.00 | ~40% | |
| total chemical synthesis | petrochemical aldehydes/alkenes | 0.00 | ~60% |
How we scored it
Where it comes from
Premium biomimetic ceramides use a yeast-fermentation-derived sphingoid base acylated with a natural fatty acid. Lower-cost mass-market ceramides are usually built by total chemical synthesis from petrochemical starting materials.
In plain English
A lipid that mimics fats naturally found in skin, used to condition skin and hair. It can be made from fermentation-derived building blocks or by chemical synthesis, so its origin varies by supplier.
CosIng definition: Ceramide 2 (Retired) is the N-acylated sphingolipid having the erythro structure that conforms generally to the formula, where m has a value ranging from 14 to 28 and n has a value ranging from 10 to 16. The INCI Name, Ceramide 2, originally developed in 1997, was designated with a retired status in 2014. For an interim period of time, trade name assignments formerly published with the INCI Name Ceramide 2 will be retained in the retired monograph, and also published with the new name assignment as either Ceramide NS or Ceramide NG.
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Structure
N-[(2S,3R)-1,3-dihydroxyoctadecan-2-yl]octadecanamide
References
- 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
- 2Ceramide 2. PubChem CID 5283573. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
- 3CERAMIDE 2. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
- 4CERAMIDE 2. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=CERAMIDE%202