Database/Hair Conditioning/Ceramide 1
100% natural origin · ISO 16128

Is Ceramide 1 natural?

Yes. All fragments, the omega-hydroxy fatty acid, linoleic acid ester, and phytosphingosine, are oleochemical or fermentation-derived, joined by mass-neutral ester/amide bonds.

INCI nameCeramide 1
CAS179186-46-0
FormulaC63H125NO6 · 992.7 Da
FunctionHair Conditioning · Skin Conditioning
FeedstockMade by esterifying a long-chain omega-hydroxy fatty acid…

How we scored it

Omega-hydroxy fatty acid esterified with natural linoleic acid, amide-bonded to phytosphingosine (fermentation-derived). Ester/amide condensation loses only water. 100% natural.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Made by esterifying a long-chain omega-hydroxy fatty acid with natural linoleic acid, then amide-coupling to phytosphingosine from yeast fermentation. No petrochemical fragment is incorporated.

In plain English

A skin-identical lipid (an older name for Ceramide EOP) that helps repair the skin barrier. Built entirely from natural fatty acids and a fermentation-derived sphingoid base.

CosIng definition: Ceramide 1 (Retired) is the N-acylated phytosphingosine having the erythro structure that conforms generally to the formula, where n has a value ranging from 10 to 20. The INCI Name, Ceramide 1, originally developed in 1997, was designated with a retired status in 2014. For an interim period of time, trade name assignments formerly published with the INCI Name Ceramide 1 will be retained in the retired monograph, and also published with the new name assignment, Ceramide EOP.

Structure

2D structure of Ceramide 1

[27-oxo-27-[[(2S,3S,4R)-1,3,4-trihydroxyoctadecan-2-yl]amino]heptacosyl] octadecanoate

PubChem CID 58418606 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Ceramide 1. PubChem CID 58418606. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3CERAMIDE 1. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4CERAMIDE 1. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=CERAMIDE%201