Database/Anti-Seborrheic/Capryloyl Glycine
100% natural origin · ISO 16128

Is Capryloyl Glycine natural?

Yes. Amide of caprylic acid and glycine; both building blocks are natural, oleochemical fatty acid and fermentation amino acid.

INCI nameCapryloyl Glycine
CAS14246-53-8
FormulaC10H19NO3 · 201.26 Da
FunctionAnti-Seborrheic · Antimicrobial
FeedstockMade by acylating glycine with caprylic acid (via…

How we scored it

Caprylic acid C8H15O- (oleochemical) + glycine (fermentation amino acid); condensation water/HCl not counted → 1.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

How it’s made

Schotten–Baumann acylation of glycine with capryloyl chloride. Each curved arrow moves one electron pair, and the film ends on the score above.

Where it comes from

Made by acylating glycine with caprylic acid (via its acid chloride) from coconut or palm kernel oil. The activation step leaves no synthetic mass in the product.

In plain English

A deodorant, anti-microbial ingredient made by combining coconut-derived caprylic acid with the amino acid glycine. Used in deodorants and skincare to help control odour-causing bacteria and oiliness.

CosIng definition: Capryloyl Glycine is the acylation product of glycine with caprylic acid chloride. It conforms to the formula:

Structure

2D structure of Capryloyl Glycine

2-(octanoylamino)acetic acid

PubChem CID 84290 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Capryloyl Glycine. PubChem CID 84290. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3CAPRYLOYL GLYCINE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4CAPRYLOYL GLYCINE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=CAPRYLOYL%20GLYCINE