How we scored it
Caproic acid (C6, coconut/palm-kernel oleochemical) amide-bonded to Tetrapeptide-3 (fermentation amino acids); both fragments natural → 1.0
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.
Where it comes from
Caproic acid fractionated from coconut or palm-kernel oil is coupled to a synthetically assembled tetrapeptide made from fermentation amino acids. No petrochemical route is used.
In plain English
A skin-protecting ingredient combining a short coconut-oil fatty acid with a chain of four amino acids. Both parts come from natural fats and fermentation, joined together in the lab.
CosIng definition: Caprooyl Tetrapeptide-3 is the product obtained by the reaction of Caproic Acid and Tetrapeptide-3
Structure
(2S)-2-[[(2S)-1-[(2S)-5-amino-2-[[2-(hexanoylamino)acetyl]amino]-5-oxopentanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoic acid
References
- 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
- 2Caprooyl Tetrapeptide-3. PubChem CID 71599291. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
- 3CAPROOYL TETRAPEPTIDE-3. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
- 4CAPROOYL TETRAPEPTIDE-3. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=CAPROOYL%20TETRAPEPTIDE-3