How we scored it
Hexanoyl (caproic acid) + four amino acids + C-terminal amide, treated as in Acetyl Hexapeptide-3; no petrochemical acetyl-type cap, so all atoms natural: 1.00.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.
Where it comes from
Dominant route: solid-phase synthesis from fermentation-derived amino acids, then acylation with caproic acid from coconut or palm-kernel oil. Supplier note: caproic acid is also made petrochemically by hexanal oxidation, so confirm the grade.
In plain English
A short peptide of four amino acids with a hexanoyl (caproic acid) fatty tail and an amidated end, used to condition skin. It is made by linking amino acids chemically and attaching the fatty acid.
CosIng definition: Caprooyl Tetrapeptide-3 Amide is the product obtained by the reaction of Caproic Acid with Tetrapeptide-3 in which the C-terminus of the peptide is an amide.
References
- 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
- 2CAPROOYL TETRAPEPTIDE-3 AMIDE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
- 3CAPROOYL TETRAPEPTIDE-3 AMIDE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=CAPROOYL%20TETRAPEPTIDE-3%20AMIDE