Database/Canthaxanthin
Route-dependent · ISO 16128

Is Canthaxanthin natural?

It depends. Commercial canthaxanthin is mostly made by total chemical synthesis from petrochemical building blocks, though natural microbial/algal sources exist at smaller scale.

INCI nameCanthaxanthin
CAS514-78-3
FormulaC40H52O2 · 564.8 Da
FeedstockMost commercial canthaxanthin is produced by total synthesis…

Why the score varies

This ingredient is made commercially by more than one route, and ISO 16128 scores the feedstock actually used. Without a supplier certificate of origin the value cannot be claimed.

RouteFeedstockNOIShareNotes
petrochemical total synthesispetrochemical carotenoid intermediates0.00majority, dominant commercial route
microbial/algal fermentation or extractionpigmented fungi, algae or bacteria1.00minority
Ask your supplier. A batch-specific certificate of origin or bio-based carbon test (ASTM D6866) settles which route applies.

How we scored it

Carotenoid pigment C40H52O2; industrial output is dominated by total petrochemical synthesis (0.0), with a minor natural/fermentation route (1.0). Exact market split uncertain.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Most commercial canthaxanthin is produced by total synthesis from petrochemical intermediates (similar to synthetic beta-carotene routes). A smaller natural-origin supply is produced by fermentation or extraction from pigmented fungi, algae or bacteria.

In plain English

An orange-red carotenoid pigment, found naturally in some mushrooms and algae but usually made by chemical synthesis for commercial use. Used as a colourant in cosmetic products.

Structure

2D structure of Canthaxanthin

2,4,4-trimethyl-3-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-3,7,12,16-tetramethyl-18-(2,6,6-trimethyl-3-oxocyclohexen-1-yl)octadeca-1,3,5,7,9,11,13,15,17-nonaenyl]cyclohex-2-en-1-one

PubChem CID 5281227 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Canthaxanthin. PubChem CID 5281227. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3CANTHAXANTHIN. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4Canthaxanthin. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=Canthaxanthin