Database/Skin Conditioning/Calcium Hexapeptide-11
100% natural origin · ISO 16128

Is Calcium Hexapeptide-11 natural?

Yes. The peptide is assembled from fermentation-derived amino acids and calcium is a mineral counter-ion, so all retained atoms are natural origin.

INCI nameCalcium Hexapeptide-11
FunctionSkin Conditioning
FeedstockDominant route is peptide synthesis or yeast-based production…

How we scored it

Hexapeptide of proteinogenic amino acids (Phe-Val-Ala-Pro-Phe-Pro) natural; calcium counter-ion mineral; no caps, so 1.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Dominant route is peptide synthesis or yeast-based production from natural amino acids, then calcium salt formation. No petrochemical fragments remain in the final molecule.

In plain English

A six-amino-acid peptide supplied as a calcium salt, added to skin products for conditioning. The amino acids are produced by fermentation and the calcium is a mineral.

CosIng definition: Calcium Hexapeptide-11 is the calcium salt of Hexapeptide-11

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2CALCIUM HEXAPEPTIDE-11. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  3. 3CALCIUM HEXAPEPTIDE-11. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=CALCIUM%20HEXAPEPTIDE-11