Why the score varies
This ingredient is made commercially by more than one route, and ISO 16128 scores the feedstock actually used. Without a supplier certificate of origin the value cannot be claimed.
| Route | Feedstock | NOI | Share | Notes |
|---|---|---|---|---|
| Caffeic acid from plant sources | hydrolysed chlorogenic acid from coffee or artichoke | 1.00 | est. 40% | |
| Synthetic caffeic acid | catechol-derived 3,4-dihydroxybenzaldehyde and malonic acid | 0.77 | est. 60% |
How we scored it
Where it comes from
Dominant route: not established; peptide-grade caffeic acid is likely synthetic (Knoevenagel condensation of 3,4-dihydroxybenzaldehyde with malonic acid), giving 0.77. Alternative: caffeic acid obtained by hydrolysing coffee or artichoke chlorogenic acid, giving 1.0.
In plain English
A five-amino-acid peptide joined to caffeic acid, a plant phenolic, used as an antioxidant, metal binder and UV absorber. The peptide comes from amino acids; the caffeic acid can be plant-derived or made synthetically.
CosIng definition: Caffeoyl Pentapeptide-27 is the product obtained by the reaction of Caffeic Acid and Pentapeptide-27.
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References
- 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
- 2CAFFEOYL PENTAPEPTIDE-27. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
- 3CAFFEOYL PENTAPEPTIDE-27. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=CAFFEOYL%20PENTAPEPTIDE-27