Database/Antimicrobial/Benzisothiazolinone
100% petroleum · ISO 16128

Is Benzisothiazolinone natural?

No. The benzothiazolone ring system is synthesised entirely from petrochemical benzene-derived intermediates.

INCI nameBenzisothiazolinone
CAS2634-33-5
FormulaC7H5NOS · 151.19 Da
FunctionAntimicrobial
FeedstockSynthesised industrially from petrochemical aromatic precursors via isothiazolinone…

How we scored it

1,2-benzothiazol-3-one built on a benzene ring via fully synthetic isothiazolinone chemistry; no natural fragment → 0/151 = 0.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Synthesised industrially from petrochemical aromatic precursors via isothiazolinone ring-closure chemistry. No natural route exists.

In plain English

A preservative that stops microbial growth in products, made entirely from synthetic petrochemical starting materials. Does not occur in nature.

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Structure

2D structure of Benzisothiazolinone

1,2-benzothiazol-3-one

PubChem CID 17520 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Benzisothiazolinone. PubChem CID 17520. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3BENZISOTHIAZOLINONE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4BENZISOTHIAZOLINONE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=BENZISOTHIAZOLINONE