Database/Antioxidant/Baicalin
100% natural origin · ISO 16128

Is Baicalin natural?

Yes. Baicalin is obtained by extraction and purification from Chinese skullcap root; its complex chiral glycoside structure is not synthesised commercially.

INCI nameBaicalin
CAS21967-41-9
FormulaC21H18O11 · 446.4 Da
FunctionAntioxidant · Skin Conditioning
FeedstockBaicalin is extracted and purified from the root…

How we scored it

Flavonoid glucuronide isolated by extraction/purification from Scutellaria baicalensis root; no viable commercial total synthesis. 1.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Baicalin is extracted and purified from the root of Scutellaria baicalensis (Chinese skullcap). No petrochemical synthesis route is used industrially.

In plain English

An antioxidant skin-conditioning compound extracted and purified from the root of Chinese skullcap. It occurs naturally in the plant and is isolated by extraction rather than synthesised.

Structure

2D structure of Baicalin

(2S,3S,4S,5R,6S)-6-(5,6-dihydroxy-4-oxo-2-phenylchromen-7-yl)oxy-3,4,5-trihydroxyoxane-2-carboxylic acid

PubChem CID 64982 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Baicalin. PubChem CID 64982. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3BAICALIN. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4BAICALIN. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=BAICALIN