Database/Antioxidant/Ascorbyl Tetraisopalmitate
100% natural origin · ISO 16128

Is Ascorbyl Tetraisopalmitate natural?

Yes. Both the ascorbic acid and the branched C16 fatty acid are assumed natural-origin for cosmetic grades.

INCI nameAscorbyl Tetraisopalmitate
CAS161436-56-2
FormulaC70H128O10 · 1129.8 Da
FunctionAntioxidant · Emollient
FeedstockMade by esterifying ascorbic acid, from fermented glucose,…

How we scored it

Ascorbic acid (natural) tetraesterified with isopalmitic acid (C16 branched fatty acid, oleochemical) → total/total = 1.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Made by esterifying ascorbic acid, from fermented glucose, with isopalmitic acid, a branched C16 fatty acid typically produced from natural fatty-acid feedstocks. A petrochemical route to isopalmitic acid also exists.

In plain English

An oil-soluble vitamin C ester used to condition skin and help protect against oxidative stress. It is made by combining ascorbic acid with isopalmitic acid, a branched fatty acid, in a four-fold ester.

CosIng definition: Ascorbyl Tetraisopalmitate is the tetraester of Ascorbic Acid and isopalmitic acid. It conforms generally to the formula:

Structure

2D structure of Ascorbyl Tetraisopalmitate

[(2S)-2-[(2R)-3,4-bis(2-hexyldecanoyloxy)-5-oxo-2H-furan-2-yl]-2-(2-hexyldecanoyloxy)ethyl] 2-hexyldecanoate

PubChem CID 10260680 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Ascorbyl Tetraisopalmitate. PubChem CID 10260680. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3ASCORBYL TETRAISOPALMITATE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4ASCORBYL TETRAISOPALMITATE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=ASCORBYL%20TETRAISOPALMITATE