Database/Skin Conditioning/Arginine Ferulate
Route-dependent · ISO 16128

Is Arginine Ferulate natural?

It depends. Fermentation-derived arginine is natural; ferulic acid is natural if rice/wheat-bran extracted, petrochemical if made from guaiacol/vanillin.

INCI nameArginine Ferulate
CAS950890-74-1
FormulaC16H24N4O6 · 368.38 Da
FunctionSkin Conditioning
FeedstockCombines fermentation-derived arginine with ferulic acid, which is…

Why the score varies

This ingredient is made commercially by more than one route, and ISO 16128 scores the feedstock actually used. Without a supplier certificate of origin the value cannot be claimed.

RouteFeedstockNOIShareNotes
natural ferulic acidrice/wheat bran extraction + fermentation arginine1.00unknown
synthetic ferulic acidguaiacol/vanillin synthesis + fermentation arginine0.47unknown
Ask your supplier. A batch-specific certificate of origin or bio-based carbon test (ASTM D6866) settles which route applies.

How we scored it

Salt of arginine (174.2 Da, natural) + ferulic acid (194.2 Da); natural-ferulic route 368.4/368.4=1.0, synthetic-ferulic route 174.2/368.4=0.47.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Combines fermentation-derived arginine with ferulic acid, which is obtained either by extraction from rice or wheat bran or by chemical synthesis from guaiacol. Cosmetic-grade material can use either ferulic acid source and the market split is unclear.

In plain English

A combination of the amino acid arginine and ferulic acid, used to condition skin. Depending on the supplier, the ferulic acid portion may come from rice bran or be made synthetically.

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Structure

2D structure of Arginine Ferulate

(2S)-2-amino-5-(diaminomethylideneamino)pentanoic acid;(E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid

PubChem CID 25059665 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Arginine Ferulate. PubChem CID 25059665. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3ARGININE FERULATE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4ARGININE FERULATE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=ARGININE%20FERULATE