Database/Antioxidant/Arctigenin
100% natural origin · ISO 16128

Is Arctigenin natural?

Yes. A plant lignan purified from burdock seed; no significant petrochemical synthetic route is used commercially for this phytochemical.

INCI nameArctigenin
CAS7770-78-7
FormulaC21H24O6 · 372.4 Da
FunctionAntioxidant
FeedstockPurified by extraction from the seeds of burdock,…

How we scored it

Dibenzylbutyrolactone lignan, C21H24O6 372.4 Da. Commercial supply is extraction/purification from burdock (Arctium lappa) seed, not petrochemical total synthesis. All carbons plant-derived, 1.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Purified by extraction from the seeds of burdock, Arctium lappa (also found in Forsythia). No commercially significant petrochemical synthesis route.

In plain English

A natural antioxidant compound purified from burdock seeds, used in skincare for its protective effects on skin cells.

Structure

2D structure of Arctigenin

(3R,4R)-4-[(3,4-dimethoxyphenyl)methyl]-3-[(4-hydroxy-3-methoxyphenyl)methyl]oxolan-2-one

PubChem CID 64981 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Arctigenin. PubChem CID 64981. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3ARCTIGENIN. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4ARCTIGENIN. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=ARCTIGENIN