Database/Antioxidant/Allantoin Ascorbate
Mostly natural · ISO 16128

Is Allantoin Ascorbate natural?

Mostly. Ascorbic acid is made from glucose by fermentation or Reichstein chemistry, while allantoin is synthesised from urea (natural-gas ammonia) and glyoxylic acid.

INCI nameAllantoin Ascorbate
CAS57448-83-6
FormulaC10H14N4O9 · 334.24 Da
FunctionAntioxidant · Skin Conditioning
FeedstockAscorbic acid from corn glucose is combined 1:1…

How we scored it

C10H14N4O9, 334.2 Da = ascorbic acid 176.1 (glucose-derived, natural) + allantoin 158.1 (urea and glyoxylic acid, petrochemical). 176.1 / 334.2 = 0.53.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Ascorbic acid from corn glucose is combined 1:1 with synthetic allantoin. Allantoin extracted from comfrey is not commercially significant.

In plain English

A molecular complex of vitamin C (ascorbic acid) and allantoin, a skin-soothing compound. It is used as an antioxidant and skin-conditioning ingredient in serums and creams.

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Structure

2D structure of Allantoin Ascorbate

(2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one;(2,5-dioxoimidazolidin-4-yl)urea

PubChem CID 67732897 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Allantoin Ascorbate. PubChem CID 67732897. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3ALLANTOIN ASCORBATE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4ALLANTOIN ASCORBATE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=ALLANTOIN%20ASCORBATE