Database/Skin Conditioning/Alkaline Phosphatase
100% natural origin · ISO 16128

Is Alkaline Phosphatase natural?

Yes. The enzyme is a protein from animal tissue or microbial fermentation, and its Zn and Mg cofactor ions are mineral, so all atoms are natural origin.

INCI nameAlkaline Phosphatase
CAS9001-78-9
FunctionSkin Conditioning
FeedstockDominant sources are calf or bovine intestinal mucosa…

How we scored it

Enzyme protein (amino acids) with Zn and Mg cofactors; animal or microbial protein, no synthetic fragments, so 1.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Dominant sources are calf or bovine intestinal mucosa and recombinant microbial fermentation (E. coli or yeast), purified by chromatography. No petrochemical route is relevant.

In plain English

An enzyme protein that removes phosphate groups from other molecules, listed here for skin conditioning. It is obtained from animal intestinal tissue or from microorganisms grown by fermentation.

CosIng definition: Alkaline Phosphatase is an enzyme that hydrolizes esters of phosphoric acid. Specfically, Alkaline Phosphatase is used to catalyze the removal of 5'-phosphates from DNA and RNA

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2ALKALINE PHOSPHATASE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  3. 3ALKALINE PHOSPHATASE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=ALKALINE%20PHOSPHATASE