Database/Skin Conditioning/Adenine
100% natural origin · ISO 16128

Is Adenine natural?

Yes. Produced by fermentation like related nucleosides; a minor HCN-oligomerisation chemical route exists but is not used commercially.

INCI nameAdenine
CAS73-24-5
FormulaC5H5N5 · 135.13 Da
FunctionSkin Conditioning
FeedstockCosmetic-grade adenine is produced by microbial fermentation of…

How we scored it

Purine base C5H5N5; cosmetic-grade material is made by microbial fermentation, same feedstock class as adenosine. 1.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Cosmetic-grade adenine is produced by microbial fermentation of sugar feedstocks. A laboratory HCN-based chemical synthesis exists but has no meaningful commercial cosmetic-ingredient supply share.

In plain English

Adenine, sometimes called vitamin B4, is a building block of DNA and RNA used to condition skin. It's produced by fermenting sugars with microorganisms.

CosIng definition: Vitamin B4

Structure

2D structure of Adenine

7H-purin-6-amine

PubChem CID 190 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Adenine. PubChem CID 190. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3ADENINE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4ADENINE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=ADENINE