Database/Skin Conditioning/Acetyl Tripeptide-30 Citrulline
Mostly natural · ISO 16128

Is Acetyl Tripeptide-30 Citrulline natural?

Mostly. Citrulline and the peptide's amino acids are fermentation/hydrolysate products; only the acetyl cap is petrochemical.

INCI nameAcetyl Tripeptide-30 Citrulline
CAS2098345-00-5
FormulaC22H41N7O9 · 547.6 Da
FunctionSkin Conditioning
FeedstockAssembled from fermentation-derived amino acids including citrulline, with…

How we scored it

Peptide/citrulline backbone (natural, amino acids) 506 Da; acetyl cap petrochemical C2H2O 42 Da; 506/548=0.92.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Assembled from fermentation-derived amino acids including citrulline, with the N-terminus capped using petrochemical acetic anhydride. No significant alternative route.

In plain English

A lab-made peptide combining citrulline, an amino acid, with a chain of other amino acids, capped with a small acetyl group. Used in skincare as a conditioning ingredient.

CosIng definition: Acetyl Tripeptide-30 Citrulline is the reaction product of acetic acid and Citrulline with Tripeptide-30

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Structure

2D structure of Acetyl Tripeptide-30 Citrulline

(2S,3S)-2-[[(2S)-4-[[(4S)-4-amino-4-carboxybutyl]carbamoylamino]oxy-2-[[(2S)-2,6-diaminohexanoyl]amino]-4-oxobutanoyl]amino]-3-methylpentanoic acid

PubChem CID 169450581 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Acetyl Tripeptide-30 Citrulline. PubChem CID 169450581. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3ACETYL TRIPEPTIDE-30 CITRULLINE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4ACETYL TRIPEPTIDE-30 CITRULLINE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=ACETYL%20TRIPEPTIDE-30%20CITRULLINE