Database/Emollient/Acetyl Proline
Mostly natural · ISO 16128

Is Acetyl Proline natural?

Mostly. Fermentation-derived proline backbone is natural; acetyl cap comes from petrochemical acetic anhydride.

INCI nameAcetyl Proline
CAS68-95-1
FormulaC7H11NO3 · 157.17 Da
FunctionEmollient
FeedstockMade by acetylating fermentation-derived L-proline with acetic anhydride.…

How we scored it

Proline backbone (115.13-1H=114.13, fermentation) + acetyl cap C2H3O (43.04, petrochemical) = 157.17. 114.13/157.17=0.73.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Made by acetylating fermentation-derived L-proline with acetic anhydride. No commercially significant alternative route exists.

In plain English

An emollient made by attaching an acetyl group to the amino acid proline, produced through fermentation. Helps skin retain moisture and feel smooth.

Natural alternatives with the same function

Structure

2D structure of Acetyl Proline

(2S)-1-acetylpyrrolidine-2-carboxylic acid

PubChem CID 66141 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Acetyl Proline. PubChem CID 66141. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3ACETYL PROLINE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4ACETYL PROLINE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=ACETYL%20PROLINE