Database/Skin Conditioning/Acetyl Glutamine
Mostly natural · ISO 16128

Is Acetyl Glutamine natural?

Mostly. Glutamine from fermentation is N-acetylated using petrochemical acetic anhydride as the capping agent.

INCI nameAcetyl Glutamine
CAS2490-97-3
FormulaC7H12N2O4 · 188.18 Da
FunctionSkin Conditioning
FeedstockL-Glutamine is produced by fermentation of glucose, then…

How we scored it

Glutamine C5H10N2O3 146.15 Da (fermentation, natural) + acetyl cap C2H2O 42.04 Da (petrochemical, acetic anhydride) = 146.15/188.18 = 0.78
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

L-Glutamine is produced by fermentation of glucose, then acetylated with acetic anhydride. Single dominant commercial route.

In plain English

A modified form of the amino acid glutamine, used to condition and support the skin's surface.

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Structure

2D structure of Acetyl Glutamine

(2S)-2-acetamido-5-amino-5-oxopentanoic acid

PubChem CID 182230 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Acetyl Glutamine. PubChem CID 182230. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3ACETYL GLUTAMINE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4ACETYL GLUTAMINE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=ACETYL%20GLUTAMINE