Database/Skin Conditioning/Acetyl Glutamic Acid
Mostly natural · ISO 16128

Is Acetyl Glutamic Acid natural?

Mostly. Fermentation-derived glutamic acid backbone is natural; the acetyl cap comes from petrochemical acetic anhydride.

INCI nameAcetyl Glutamic Acid
CAS1188-37-0
FormulaC7H11NO5 · 189.17 Da
FunctionSkin Conditioning
FeedstockMade by acetylating fermentation-derived L-glutamic acid with acetic…

How we scored it

Glutamic acid backbone (147.13-1H=146.12, fermentation) + acetyl cap C2H3O (43.04, from acetic anhydride, petrochemical) = 189.16. 146.12/189.17=0.77.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Made by acetylating fermentation-derived L-glutamic acid with acetic anhydride. The acetyl group is a petrochemical-derived cap; no alternative route is commercially significant.

In plain English

A modified amino acid used to condition skin, made by attaching an acetyl group to glutamic acid, itself produced by fermenting sugars. Most of its weight is natural.

Natural alternatives with the same function

Structure

2D structure of Acetyl Glutamic Acid

(2S)-2-acetamidopentanedioic acid

PubChem CID 70914 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Acetyl Glutamic Acid. PubChem CID 70914. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3ACETYL GLUTAMIC ACID. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4ACETYL GLUTAMIC ACID. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=ACETYL%20GLUTAMIC%20ACID