Database/Hair Conditioning/Acetyl Dipeptide-1 Cetyl Ester
Mostly natural · ISO 16128

Is Acetyl Dipeptide-1 Cetyl Ester natural?

Mostly. Tyrosine and arginine are fermentation/hydrolysate amino acids, cetyl is an oleochemical fatty alcohol; only the acetyl cap is petrochemical.

INCI nameAcetyl Dipeptide-1 Cetyl Ester
CAS196604-48-5
FormulaC33H57N5O5 · 603.8 Da
FunctionHair Conditioning · Skin Conditioning
FeedstockMade by coupling fermentation-derived tyrosine and arginine, esterifying…

How we scored it

Dipeptide (Tyr+Arg, natural) + C16 cetyl ester (natural fatty alcohol) = 562 Da; acetyl cap petrochemical C2H2O = 42 Da; 562/604=0.93.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Made by coupling fermentation-derived tyrosine and arginine, esterifying with oleochemical cetyl alcohol, and capping the amine with a small petrochemical acetyl group. No significant alternative route.

In plain English

A lab-made peptide of two amino acids attached to a fatty alcohol from vegetable oil, with a small acetyl cap. Used in skin and hair products to condition and moisturise.

CosIng definition: Tyrosine acetate and arginine, hexadecyl ester, dipeptide

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Structure

2D structure of Acetyl Dipeptide-1 Cetyl Ester

hexadecyl (2S)-2-[[(2S)-2-acetamido-3-(4-hydroxyphenyl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoate

PubChem CID 11685829 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Acetyl Dipeptide-1 Cetyl Ester. PubChem CID 11685829. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3ACETYL DIPEPTIDE-1 CETYL ESTER. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4ACETYL DIPEPTIDE-1 CETYL ESTER. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=ACETYL%20DIPEPTIDE-1%20CETYL%20ESTER