Database/Hair Dyeing/4-Hydroxypropylamino-3-Nitrophenol
100% petroleum · ISO 16128

Is 4-Hydroxypropylamino-3-Nitrophenol natural?

No. Built entirely on a petrochemical phenol/aniline ring with nitro and hydroxypropylamino substituents; no natural fragment.

INCI name4-Hydroxypropylamino-3-Nitrophenol
CAS92952-81-3
FormulaC9H12N2O4 · 212.20 Da
FunctionHair Dyeing
FeedstockManufactured industrially by nitration and hydroxypropylamination of a…

How we scored it

Whole molecule is a synthetic nitrophenol/aminophenol hair-dye intermediate; benzene ring is a petrochemical fragment → 0/212.20 = 0.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Manufactured industrially by nitration and hydroxypropylamination of a petrochemical nitrophenol/nitrochlorobenzene precursor. Used solely as an oxidative hair-dye coupler; no natural route exists.

In plain English

A synthetic dye ingredient used in permanent and semi-permanent hair colour products to help build warm and red shades.

Natural alternatives with the same function

Beta Vulgaris Root Powder 100% natural origin

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 Epicatechin 100% natural origin

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 Lawsonia Inermis Extract 100% natural origin

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 Pyrogallol 100% natural origin

A hair-dye ingredient traditionally made by heating gallic acid, itself extracted from plant tannins in gallnuts, until it…

Structure

2D structure of 4-Hydroxypropylamino-3-Nitrophenol

4-(3-hydroxypropylamino)-3-nitrophenol

PubChem CID 5463795 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 24-Hydroxypropylamino-3-Nitrophenol. PubChem CID 5463795. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 34-HYDROXYPROPYLAMINO-3-NITROPHENOL. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 44-HYDROXYPROPYLAMINO-3-NITROPHENOL. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=4-HYDROXYPROPYLAMINO-3-NITROPHENOL