Database/Hair Dyeing/2-Hydroxyethylamino-5-Nitroanisole
100% petroleum · ISO 16128

Is 2-Hydroxyethylamino-5-Nitroanisole natural?

No. The nitroanisole aromatic ring and hydroxyethylamino chain are built entirely from petrochemical benzene/phenol derivatives.

INCI name2-Hydroxyethylamino-5-Nitroanisole
CAS66095-81-6
FormulaC9H12N2O4 · 212.20 Da
FunctionHair Dyeing
FeedstockSynthesized from petrochemical anisole/nitrobenzene intermediates via nitration and…

How we scored it

2-(2-methoxy-4-nitroanilino)ethanol: nitroanisole aromatic core + ethanolamine chain, entirely petrochemical (benzene/phenol derivative) → 0.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Synthesized from petrochemical anisole/nitrobenzene intermediates via nitration and amination with ethylene oxide. No natural or alternative route exists for this hair-dye intermediate.

In plain English

A synthetic dye intermediate used in semi-permanent and permanent hair colourants to produce orange-red shades. It's manufactured from petrochemical aromatic compounds.

Natural alternatives with the same function

Structure

2D structure of 2-Hydroxyethylamino-5-Nitroanisole

2-(2-methoxy-4-nitroanilino)ethanol

PubChem CID 3017645 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 22-Hydroxyethylamino-5-Nitroanisole. PubChem CID 3017645. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 32-HYDROXYETHYLAMINO-5-NITROANISOLE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 42-HYDROXYETHYLAMINO-5-NITROANISOLE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=2-HYDROXYETHYLAMINO-5-NITROANISOLE