Database/Hair Dyeing/2-Chloro-p-Phenylenediamine Sulfate
Mostly petroleum · ISO 16128

Is 2-Chloro-p-Phenylenediamine Sulfate natural?

Mostly not. The chlorinated phenylenediamine ring is a petrochemical benzene derivative; the sulfate/sulfuric-acid counter-ion is mineral-derived natural mass.

INCI name2-Chloro-p-Phenylenediamine Sulfate
CAS6219-71-2
FormulaC6H9ClN2O4S · 240.67 Da
FunctionHair Dyeing
FeedstockManufactured by chlorination and amination of petrochemical benzene,…

How we scored it

Chlorophenylenediamine free base (142.59 Da, petrochemical) + H2SO4 (98.08 Da, mineral, natural) → 98.08/240.67 = 0.41.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Manufactured by chlorination and amination of petrochemical benzene, then isolated as the sulfate salt with mineral sulfuric acid. No natural route exists for the aromatic core.

In plain English

A synthetic hair-dye intermediate that reacts with a developer to build permanent hair colour.

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 Pyrogallol 100% natural origin

A hair-dye ingredient traditionally made by heating gallic acid, itself extracted from plant tannins in gallnuts, until it…

Structure

2D structure of 2-Chloro-p-Phenylenediamine Sulfate

2-chlorobenzene-1,4-diamine;sulfuric acid

PubChem CID 22584 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 22-Chloro-p-Phenylenediamine Sulfate. PubChem CID 22584. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 32-CHLORO-P-PHENYLENEDIAMINE SULFATE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 42-CHLORO-P-PHENYLENEDIAMINE SULFATE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=2-CHLORO-P-PHENYLENEDIAMINE%20SULFATE