Is 2-Amino-4-Nitrophenol natural? NOI 0.00

Q: Is 2-Amino-4-Nitrophenol natural?

2-Amino-4-Nitrophenol has a Natural Origin Index (NOI) of 0.00 (scale 0–1) per ISO 16128. Made by nitration/amination of petrochemical phenol; no natural feedstock or commercial route exists. An NOI of 0.00 means 0% of its molecular mass is traceable to a natural, renewable source.

How we scored it

Synthetic aromatic nitroaminophenol, C6H6N2O3; entire molecule built from petrochemical phenol feedstock -> 0.0.

What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Manufactured industrially from petroleum-derived phenol via nitration and reduction steps. Used as a hair-dye intermediate; no natural alternative route exists.

In plain English

A synthetic dye intermediate derived from petroleum-based phenol, used in permanent hair dyes to develop colour; not a natural ingredient.

Structure

2-amino-4-nitrophenol

PubChem CID 3613389 ↗

References

1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
22-Amino-4-Nitrophenol. PubChem CID 3613389. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
32-AMINO-4-NITROPHENOL. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
42-Amino-4-nitrophenol. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=2-Amino-4-nitrophenol