Database/Hair Dyeing/2,4-Diaminophenoxyethanol HCl
Mostly petroleum · ISO 16128

Is 2,4-Diaminophenoxyethanol HCl natural?

Mostly not. The diaminophenoxyethanol backbone is a wholly synthetic aromatic-amine hair-dye intermediate; only the chloride counter-ion is mineral-derived.

INCI name2,4-Diaminophenoxyethanol HCl
CAS66422-95-5
FormulaC8H14Cl2N2O2 · 241.11 Da
FunctionHair Dyeing
FeedstockManufactured from petrochemical aromatic-amine chemistry (nitration/reduction routes), then…

How we scored it

Free base C8H12N2O2 168Da petrochemical (synthetic aromatic diamine ether); 2 Cl 71Da natural mineral counter-ion -> 71/241 = 0.29.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Manufactured from petrochemical aromatic-amine chemistry (nitration/reduction routes), then isolated as the hydrochloride salt. No natural production route for the organic backbone exists.

In plain English

A hair-dye intermediate that develops colour on the hair shaft. The colour-forming molecule is entirely synthetic; only its small chloride salt component is mineral-derived.

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Structure

2D structure of 2,4-Diaminophenoxyethanol HCl

2-(2,4-diaminophenoxy)ethanol;dihydrochloride

PubChem CID 47932 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 22,4-Diaminophenoxyethanol HCl. PubChem CID 47932. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 32,4-DIAMINOPHENOXYETHANOL HCL. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 42,4-DIAMINOPHENOXYETHANOL HCL. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=2%2C4-DIAMINOPHENOXYETHANOL%20HCL