Database/Skin Conditioning Agent/Sodium Levulinate
100% natural origin · ISO 16128

Is Sodium Levulinate natural?

Yes. Cosmetic-grade levulinic acid is made by acid hydrolysis of biomass sugars (corn, sugarcane bagasse) and neutralised with sodium hydroxide; a petrochemical maleic-anhydride route exists but is not used for personal care grades.

INCI nameSodium Levulinate
CAS19856-23-6
FormulaC5H7NaO3 · 138.10 Da
FunctionSkin Conditioning Agent · Humectant
FeedstockBiomass-derived levulinic acid (GFBiochemicals, Biofine process) neutralised with…

How we scored it

What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

How it’s made

Levulinic acid + NaOH (neutralisation). Each curved arrow moves one electron pair, and the film ends on the score above.

Where it comes from

Biomass-derived levulinic acid (GFBiochemicals, Biofine process) neutralised with sodium hydroxide. Confirm bio-based origin with the supplier.

Sodium levulinate is the sodium salt of levulinic acid. The synthesis typically involves two main stages: the production of levulinic acid and its subsequent neutralization with a sodium base.

Levulinic acid production from renewable sources involves the acid-catalyzed dehydration of hexose sugars (like glucose or fructose) or polysaccharides (like cellulose or starch). This process often uses mineral acids such as sulfuric acid or hydrochloric acid at elevated temperatures (typically 150-200°C) under pressure. The reaction breaks down the carbohydrates, forming levulinic acid and formic acid as byproducts. The reaction mixture is then cooled, and levulinic acid is separated and purified through techniques like extraction, distillation, or crystallization.

Alternatively, levulinic acid can be synthesized from petrochemical precursors, though this route is less prevalent for cosmetic applications due to the increasing demand for natural and renewable ingredients. The specific petrochemical routes are varied and often proprietary, but they generally involve multi-step syntheses starting from petroleum-derived building blocks.

Once levulinic acid is obtained and purified, it is neutralized with a sodium-containing base, most commonly sodium hydroxide (NaOH) or sodium carbonate (Na2CO3), in an aqueous solution. The reaction is a simple acid-base neutralization: C5H8O3 (levulinic acid) + NaOH -> C5H7O3Na (sodium levulinate) + H2O. The reaction is typically carried out at moderate temperatures. The resulting sodium levulinate solution is then concentrated, and the solid product can be obtained through evaporation and drying, or it can be used directly as an aqueous solution.

In plain English

Sodium levulinate is a versatile ingredient often found in skincare products. It's known for its ability to help condition the skin, making it feel smoother and softer. It also acts as a humectant, meaning it helps attract and retain moisture in the skin, contributing to hydration.

This ingredient is valued for its natural origin. It's derived from levulinic acid, which can be produced from plant-based materials like corn or sugarcane. This makes it a popular choice for brands looking to offer more sustainable and naturally-derived formulations. Its production process involves converting plant sugars into levulinic acid, which is then neutralized with a sodium compound to create the final ingredient.

CosIng definition: Sodium Levulinate is the sodium salt of Levulinic Acid.

Structure

2D structure of Sodium Levulinate

sodium 4-oxopentanoate

PubChem CID 23662139 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Sodium Levulinate. PubChem CID 23662139. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3SODIUM LEVULINATE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4SODIUM LEVULINATE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=SODIUM%20LEVULINATE