Retinol has a Natural Origin Index (NOI) of 0.00 (scale 0–1) per ISO 16128. Retinol is exclusively synthesized from petrochemical feedstocks, resulting in a Natural Origin Index (NOI) of 0.0. An NOI of 0.00 means 0% of its molecular mass is traceable to a natural, renewable source.

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100% Petroleum · ISO 16128

Is Retinol Natural?

Learn about Retinol — its natural origin index (ISO 16128), feedstock sources, synthesis process, and renewability classification.

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Natural Origin Index

INCI NameRetinol

IUPAC Name(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraen-1-ol

FormulaC20H30O

PubChem CID445354 ↗

FunctionSkin Conditioning Agent · Antioxidant

FeedstockThe primary commercial feedstock for

Chemical Structure

Learn about Retinol — its natural origin index (ISO 16128), feedstock sources, synthesis process, and renewability classification.

View full data on PubChem ↗

Quick Facts

INCI NameRetinol
IUPAC Name(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraen-1-ol
Molecular FormulaC20H30O
PubChem CID445354 ↗
FunctionsSkin Conditioning AgentAntioxidant
Primary FeedstockThe primary commercial feedstock for retinol synthesis is derived from petrochemical sources, typically involving cholesterol or other sterols that are ultimately traced back to petroleum. While alternative routes exist, the dominant industrial production relies on synthetic pathways originating from non-renewable resources.
NOI Score0.0 / 1.0
Tier100% Petroleum

Description

Learn about Retinol — its natural origin index (ISO 16128), feedstock sources, synthesis process, and renewability classification.

References

1ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products — Part 2. ISO, Geneva.
2Retinol. National Center for Biotechnology Information. PubChem CID 445354. pubchem.ncbi.nlm.nih.gov ↗