Synthesis Routes
Why the score varies
This ingredient can be manufactured via multiple distinct synthesis pathways — some starting from petroleum feedstocks, others from renewable biological sources. ISO 16128-2 assigns the NOI based on the actual feedstock used, which means the score depends entirely on which route your specific supplier uses.
Without supplier documentation, this ingredient cannot be claimed as renewable. Certification requires verified feedstock provenance.
| Synthesis Route | Feedstock | NOI | Market Share | Notes |
|---|---|---|---|---|
| Petrochemical synthesis | 3-Cyanopyridine (petroleum-derived pyridine) | 0.0 | Dominant industrial route; 3-cyanopyridine hydrolyzed to nicotinamide; fully petroleum-derived | |
| Bio-fermentation | Glucose (corn or sugarcane-derived) | 1.0 | Emerging commercial route using engineered microorganisms; fully renewable when bio-based certified |
Chemical Structure
Learn about Niacinamide — its natural origin index (ISO 16128), feedstock sources, synthesis process, and renewability classification.
View full data on PubChem ↗Quick Facts
- INCI NameNiacinamide
- IUPAC Namepyridine-3-carboxamide
- Molecular FormulaC6H6N2O
- PubChem CID936 ↗
- FunctionsSkin conditioning agentAntioxidantHair conditioning agentHumectant
- Primary FeedstockNiacinamide is typically synthesized from petrochemical-derived precursors. The primary starting materials are often pyridine and ammonia, both of which are ultimately sourced from fossil fuels like natural gas or petroleum. While some alternative synthesis routes might explore bio-based pathways, the dominant industrial production relies on these non-renewable feedstocks.
- NOI Score0.0 / 1.0
- TierRoute-Dependent
Description
Learn about Niacinamide — its natural origin index (ISO 16128), feedstock sources, synthesis process, and renewability classification.
References
- 1ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products — Part 2. ISO, Geneva.
- 2Niacinamide. National Center for Biotechnology Information. PubChem CID 936. pubchem.ncbi.nlm.nih.gov ↗